Randy Pausch is a Carnegie Mellon computer science professor who has created
innovative software systems,
interactive virtual worlds and designed theme park rides for Disney, is dying of pancreatic cancer. As part of a series of lectures that professors would give if they knew it would be their last, he gives his last lecture. I saw snippets of it
here in a WSJ video report of the lecture. It was pretty brilliant. Here is the lecture in it's entirety -- 1 hour 44 minutes: